$3B SWFL nonprofit health care system names CEO

Following a national search, a Fort Myers nonprofit health system has appointed its next leader — someone who has worked for the organization for more than 30 years. Lee Health COO Ben Spence has been named the system's next president and CEO, effective Oct. 1.

Spence will succeed Dr. Larry Antonucci, who announced his plans to retire Sept. 30 from the roles of president and CEO after nine years with Lee Health. The Lee Health board approved Spence's appointment June 4, following a search in partnership with Chicago search firm Heidrick & Struggles.

Lee Health is one of the largest nonprofit medical organizations in Florida, with $3 billion in operating revenue in fiscal 2024. It has nearly 15,000 employees. 

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“The Board conducted a thoughtful and highly competitive national search that included exceptional candidates from across the country,” Lee Health Board of Directors Chair Joseph Catti says in a statement. “Throughout the process, Ben distinguished himself through his deep understanding of our mission, proven leadership experience and clear vision for the future of healthcare in Southwest Florida.”

Spence's career at Lee Health has spanned more than three decades, the release states. He began working for the organization in 1995 as a reimbursement clerk and since 2000, has held leadership roles across finance, strategy and operations. In 2014, he became CFO and held that title until he was promoted to COO in 2025.

"This organization has shaped my career and my understanding of what it means to serve a community through healthcare,” Spence says in a statement. “I am grateful to the board for its confidence and to the leaders, physicians, team members and volunteers who make our mission possible every day. Together, we will continue building on Lee Health's strong foundation while advancing the exceptional care and services our patients and communities depend on."

Until Antonucci retires, Spence will continue in his role as COO while working with executive leadership and the board on the transition.