Moffitt Cancer Center, Tampa hotel operator partner on $84M project

Moffitt Cancer Center and Mainsail Lodging & Development are planning a 200-room hotel to open in 2028.

The hotel will be on the cancer institute’s McKinley Campus just south of East Fowler Avenue in Tampa. It will also serve Moffitt’s nearby Magnolia campus at the University of South Florida.

In a statement Thursday, Moffitt and the Tampa hotel developer say the $84 million project addresses “a longstanding need for modern, high-quality accommodations” near the medical campuses.

As far as the hotel flag, a Moffitt spokesperson, in a Thursday email, says the developers "are currently in negotiations with a well recognized national brands that compliments the rest of their portfolio." Officials expect to have an announcement on the brand, with exterior renderings, by the end of 2025, the spokesperson adds.

Data, according to the statement, shows Moffitt generates more than 68,000 room nights in the Tampa Bay region each year. The hotel is expected to support nearly half the demand.

When complete, the hotel will include meeting and event space and a full-service restaurant and bar.

Tampa-based Mainsail’s portfolio includes the Epicurean Hotel in Tampa, the historic Fenway Hotel in Dunedin and the Luminary Hotel and Co. in downtown Fort Myers.

It also manages Innovation Hotel, a purpose-built property on the campus of Arthrex in Naples.